Cat No.R-070
Product TypeGrowth factor
Molecular Weight46.0 kDa
SterilityNegative
MyCoplasmaNegative
Purity>98%, as determined by SDS-PAGE quantitative densitometry
Expression SystemE. coli cells
FormulationLyophilized from acetonitrile and TFA with trehalose and other protectants as needed.
ReconstitutionPlease refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.
Shipping InfoIce
Stability & StorageStore frozen at -20 °C (short-term) or -80°C (long-term)

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Description

Recombinant Human Noggin Protein, Tag-Free is a BMP antagonist that binds BMP2/4/7 to block receptor engagement and downstream SMAD signaling. Essential in intestinal organoids (with R‑spondin + EGF) to maintain LGR5+ stem cells; promotes neural induction in cerebral organoids; supports kidney, prostate, and gastric models requiring BMP inhibition. Enables controlled lineage specification alongside Wnt/TGF‑β cues. Produced animal‑origin‑free for reproducible organoid maintenance.

Specifications & Applications

Application

For research use only.

Tags

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Whether you're exploring disease mechanisms or screening novel therapeutics, OgCelix is your trusted partner.

Let's build the future of translational research together.

Let's Talk Now