Recombinant Proteins for Organoid Culture
| Cat No. | R-076 |
| Product Type | Growth factor |
| Molecular Weight | 16.5 kDa |
| Sterility | Negative |
| MyCoplasma | Negative |
| Purity | ≥ 97 % as determined by SDS-PAGE |
| Expression System | Human 293 cells (HEK293) |
| Formulation | Lyophilized from sterile PBS, pH7.4, with 5% - 8% trehalose, mannitol, and 0.01% Tween80 as protectants. |
| Reconstitution | Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions. |
| Shipping Info | Ice |
| Stability & Storage | Store frozen at -20 °C (short-term) or -80°C (long-term) |
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Recombinant Human basic FGF/FGF2 Protein, Tag-Free is a member of the fibroblast growth factor family involved in bone healing, cartilage repair, bone regeneration, and nerve regeneration. FGF-2 also acts as a mitotic promoter, accelerating cell proliferation. It regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For instance, FGF-2 participates in the JAK-STAT signaling pathway to regulate cartilage metabolism and activates the ERK signaling pathway to promote cartilage regeneration. Additionally, FGF-2 in combination with FGFR1/3 promotes both the degeneration and repair of articular cartilage. FGF-2 is also a known carcinogen in GBM (glioblastoma multiforme), contributing to glioma growth and vascularization.
For research use only.
Whether you're exploring disease mechanisms or screening novel therapeutics, OgCelix is your trusted partner.
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Whether you're exploring disease mechanisms or screening novel therapeutics, OgCelix is your trusted partner.
Let's build the future of translational research together.
