Cat No.R-092
Product TypeGrowth factor
Molecular Weight52.5 kDa
SterilityNegative
MyCoplasmaNegative
Purity≥ 95 % as determined by SDS-PAGE; ≥ 95 % as determined by SEC-HPLC
Expression SystemHuman 293 cells (HEK293)
FormulationLyophilized from sterile PBS, pH7.4, with 5% - 8% trehalose, mannitol, and 0.01% Tween80 as protectants.
ReconstitutionPlease refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.
Shipping InfoIce
Stability & StorageStore frozen at -20 °C (short-term) or -80°C (long-term)

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Description

Recombinant Human DKK-1 Protein, hFc Tag is a Wnt antagonist that binds LRP5/6 to inhibit canonical Wnt signaling. In organoid systems, DKK‑1 is used to control Wnt gradients in intestinal, gastric, and tumor organoids, and to study epithelial differentiation. Fc fusion provides stability and extended activity, making it useful in long‑term culture experiments. Produced at high purity for consistent Wnt modulation.

Specifications & Applications

Application

For research use only.

Tags

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Whether you're exploring disease mechanisms or screening novel therapeutics, OgCelix is your trusted partner.

Let's build the future of translational research together.

Let's Talk Now