Recombinant Human Noggin/NOG Protein , hFc Tag R-099

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Cat No.	R-099
Product Type	Growth factor
Molecular Weight	49.8 kDa
Sterility	Negative
MyCoplasma	Negative
Purity	≥ 95 % as determined by SDS-PAGE
Expression System	Human 293 cells (HEK293)
Formulation	Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5 with 5% - 8% trehalose, mannitol, and 0.01% Tween80 as protectants.
Reconstitution	Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.
Shipping Info	Ice
Stability & Storage	Store frozen at -20 °C (short-term) or -80°C (long-term)

AcceGen Frozen Cells & Cell Lines 1 vial

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Description

Recombinant Human Noggin/NOG Protein , hFc Tag is a BMP antagonist fused to Fc for stability and extended activity. In organoid media, it is essential with R‑spondin and EGF for intestinal organoids, and also supports cerebral, kidney, and prostate organoids. Fc fusion prolongs bioactivity, reducing feeding frequency. Validated to reproducibly inhibit BMP signaling in 3D systems.

Specifications & Applications

Application

For research use only.

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