3D Ready Organoid
| Cat No. | C-024 |
| Organism | Human |
| Tissue | Midbrain |
| Disease | Normal |
| Growth Properties | Embedded 3D Culture |
| Biosafety Level | 1 |
| Growth conditions | 37℃, 95% Air, 5% CO2 |
| Size/Quantity | 1 |
| Product format | Frozen |
| Shipping Info | Dry Ice |
| Storage conditions | Liquid Nitrogen |
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Human iPSC-Derived Midbrain Organoid derived from human induced pluripotent stem cell lines represent complex three-dimensional tissue models that mimic in vivo cell-cell interactions within the midbrain. Scanning electron microscopy (SEM) images reveal organoids composed of spherical, healthy cells predominantly consisting of healthy neuronal cells, with maturation timelines highly aligned with human cortical development. By the 4-month stage, the organoids show significant maturation, with dopaminergic neurons starting to form functional networks. This stage is suitable for studying dopamine neuron maturation and investigating neurodegenerative diseases, providing a more advanced model for therapeutic research compared to earlier stages. Organoids are rigorously tested for mycoplasma, bacteria, fungi/yeast, and verified for identity, genetic stability, and functional performance.
Embedded 3D Culture
All test negative for mycoplasma, bacteria, yeast, and fungi.
For research use only. Human iPSC-Derived Midbrain Organoids are three-dimensional cell models generated from human induced pluripotent stem cells (iPSCs) using directed differentiation techniques. These organoids closely mimic the structure and function of human organs, exhibiting self-organizing properties and biological behaviors similar to real tissues. They undergo rigorous quality control to ensure high fidelity, scalability, and genetic stability, making them ideal models for a wide range of biomedical research and applications.These 3D in vitro models replicate the cellular composition of the brain and highly express the dopaminergic neuron marker TH as well as the dopaminergic progenitor cell markers FOXA2 and OTX2. In addition, brain organoids also have functional characteristics such as spontaneous neuronal activity.
Whether you're exploring disease mechanisms or screening novel therapeutics, OgCelix is your trusted partner.
Let's build the future of translational research together.
Whether you're exploring disease mechanisms or screening novel therapeutics, OgCelix is your trusted partner.
Let's build the future of translational research together.
