Human Bile Duct Cancer Organoid

Description

Human Bile Duct Cancer Organoid is a 3D tissue model derived from human cholangiocarcinoma (CCA) tissues, accurately replicating the structure and function of the bile duct. These organoids retain the molecular characteristics and tumor heterogeneity of the original cancer, including key features such as IDH1/2 mutations, FGFR2 fusion, and the differentiation of cholangiocytes. They provide a physiologically relevant platform for studying intrahepatic and extrahepatic cholangiocarcinoma, tumor progression, and chemoresistance. Human bile duct cancer organoids are ideal for disease modeling, drug testing, and investigating therapeutic response to drugs such as gemcitabine and cisplatin. These organoids undergo rigorous testing for mycoplasma, bacteria, fungi/yeast, and are verified for identity, genetic stability, and functional performance.