Recombinant Human R-Spondin 1 (21-146) Protein, Fc Tag R-007

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Cat No.	R-007
Product Type	Growth factor
Molecular Weight	40.2 kDa
Sterility	Negative
MyCoplasma	Negative
Purity	≥ 95% as determined by SDS-PAGE
Expression System	Human 293 cells (HEK293)
Formulation	Lyophilized from 0.22 μm filtered solution in 52 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Reconstitution	Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.
Shipping Info	Ice
Stability & Storage	Store frozen at -20 °C (short-term) or -80°C (long-term)

AcceGen Frozen Cells & Cell Lines 1 vial

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Description

Recombinant Human R-Spondin 1 (21-146) Protein, Fc Tag is a bioactive fragment fused with an Fc domain to enhance stability and potency. R-Spondin 1 amplifies Wnt/β-catenin signaling by binding to LGR receptors and neutralizing RNF43/ZNRF3. It is a core component of organoid media, essential for sustaining intestinal and gastric stem cell populations and enabling long-term epithelial organoid expansion. The Fc tag ensures stability and reproducibility, making it a standard supplement for organoid culture and Wnt pathway research.

Specifications & Applications

Application

For research use only.

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